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Profile of the Director


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 Prof. Mike Yaw Osei-Atweneboana 

 Director, CSIR-Water Research Institute


Prof. Mike Yaw Osei-Atweneboana is the Director of CSIR-Water Research Institute, he is a Principal Research Scientist with the Bio-Medical and Public Health Research Unit of the Institute. He is an Associate Professor of the CSIR-College of Science and Technology, Accra. Prof. Osei-Atweneboana obtained his PhD at McGill University, Canada in 2008. He is a Public Health Scientist and Molecular Geneticist, with varied and vast expertise in the areas of Medical parasitology, epidemiology, medical entomology and Molecular Genetics. He has over 20 years research experience in prevention and control of infectious diseases, including water related diseases. His research focuses on: drug efficacy and parasitological responses of pathogens to chemotherapeutic agents for control of Neglected Tropical Diseases (NTDs); development of strategies for control and elimination of NTDs; development of molecular diagnostic tools for detection of pathogens to facilitate monitoring and surveillance of NTDs; investigation into mechanisms and genetics of drug resistance and development of molecular genetic markers for detection of drug resistance in various disease systems. He has employed molecular genetic tools in various systems including fish genetics, fish diseases as well as antimicrobial resistance. He has supervised numerous post-graduate students at both PhD and master’s levels in Ghanaian and International Universities. He is an external examiner for some Universities and reviewer for international peer-reviewed journals. He has obtained many donor funded research grants from various funding agencies including the Wellcome Trust, Royal Society and Leverhulme Trust, WHO/TDR, DFID, EDCTP, MRC. He has served and continue to serve on a number of National and International Technical Committees, including WHO experts’ committees, WHO Advisor on Disease-specific Reference Group, Boards of Research and Academic Institutions as well as Governmental Institutions. He has over 80 publications including 50 peer-reviewed journals in prestigious journals such as The Lancet, Proceeding of National Academy of Sciences, USA, Plos NTDs, Journal of Clinical infectious diseases etc. Some of the achievements of Prof. Osei-Atweneboana includes the establishment and nurturing of the Bio-Medical and Public Health Research Unit of the CSIR-WRI, Institutional Review Board of the CSIR, and the Animal Care and Use Committee of the CSIR.



1. Minetti, C., Tettevi, E.J., Mechan, F., Prada, J.M., Idun, B., Biritwum,N-K., Osei-Atweneboana, M.Y., Reimer, L.J (2019). Elimination within reach: a cross-sectional study highlighting the factors that contribute to persistent lymphatic filariasis in eight communities in rural Ghana
. PLOS Neglected Tropical Diseases

2. Campbell, S.J., Osei-Atweneboana, M.Y., Stothard, D.R., Koukounari, A., Cunningham, L.J., Armoo, S., Biritwum, N.K., Gyapong, M., MacPherson, E., Theobald, S., Woode, M.E., Khan, J., Niessen, L., Adams, R.E. (2018) The COUNTDOWN Study Protocol for Expansion of Mass Drug Administration Strategies against Schistosomiasis and Soil-Transmitted Helminthiasis in Ghana. Trop. Med. Infect. Dis. 2018, 3, 10

3. Cunningham, L.J., Stothard, J., Osei-Atweneboana, M.Y., Armoo, S., Verweji, J.J., Emily R. Adams, E.R (2018). Developing a real-time PCR assay based on multiplex high-resolution melt-curve analysis: a pilot study in detection and discrimination of soil-transmitted helminth and schistosome species, Parasitology, 1-6. doi: 10.1017/S0031182018001361

4. Cunningham, L.J., Odoom, J., Pratt, D., Boatemaa L., Asante-Ntim, N., Attiku, K., Banahene, B., Osei-Atweneboana, M.Y. et al. (2018) Expanding molecular diagnostics of helminthiasis: Piloting use of the GPLN platform for surveillance of soil transmitted helminthiasis and schistosomiasis in Ghana. PLoS Negl TropDis 12 (1):e0006129.https://org/10.1371/journal.pntd.0006129

5. Stothard, R, J., Campbell, S.J., Osei-Atweneboana, M.Y., Durant, T., Stanton, M.C., Biritwum, N-K., Rollinso, D., Eloundou, D., Ombede, D.R.E., Tchuem-Tchuenté, L-A. (2017) Towards interruption of schistosomiasis transmission in sub-Saharan Africa: developing an appropriate environmental surveillance framework to guide and to support ‘end game’ interventions. Infectious Diseases of Poverty 6:10 DOI 10.1186/s40249-016-0215-9

6. Doyle, S.R., Bourguinat, C., Nana-Djeunga, H. C., Kengne-Ouafo, J.A., Pion S.D.S., Bopda, J., Kamgno J., Wanji S., Che H., Kuesel A.C., Walker M., Basáñez M-G., Boakye D.A., Osei-Atweneboana, M.Y., et al. (2017) Genome-wide analysis of ivermection response by Onchocerca volvulus reveals that genetic drift and soft selective sweeps contribute to loss of drug sensitivity. PLos neglected tropical diseases11(e0005816) 7

7. Armoo, S. Doyle, S.R., Osei-Atweneboana, M.Y., Grant, W.N. (2017) Significant heterogeneity in Wolbachia copy number within and between populations of Onchocerca volvulus. Parasites & vectors10(188)1

8. Doyle, S.R., Armoo, S., Renz, A., Taylor, M.J., Osei-Atweneboana, M.Y.,   Warwick, N.G (2016) Discrimination between Onchocerca volvulus and O. ochengi filarial larvae in Simulium damnosum s.l. and their distribution throughout central Ghana using a versatile high-resolution speciation assay. Parasites & Vectors, 9-536. DOI.1186/sl3071-1832-7 

9. Frempong, K. K., Walker, M., Cheke, R. A., Tetevi, E. J., Gyan, E.T., Owusu, E. O., Wilson, M. D., Boakye, D. B., Taylor, M. J., Biritwum, N.K., Osei-Atweneboana, M.Y et al. (2016) Does Increasing Treatment Frequency Address Suboptimal Responses to Ivermectin for the Control and Elimination of River Blindness?  Clin. Infect. Dis, 62(11):1338–47. doi: 10.1093/cid/ciw144

10. Alhassan, A., Osei-Atweneboana, M.Y., Kyeremeh, K.F., Poole, C.B., Li, Z., Tettevi, E.J., Tanner, N.A., Carlow, C.K.S. (2016). Comparison of a new visual isothermal nucleic acid amplification test with PCR and skin snip analysis for diagnosis of onchocerciasis in human. Mol Bio Parasit

11. Lamberton, P.H.L., Cheke, R.A., Walker, M., Winskill, P., Crainey, J. L., Boakye, D. A., Osei-Atweneboana, M.Y., Tirados I., Wilson, D,M., Tetteh-Kumah, A., Otoo, S., Post R.J., Basañez,M.G. (2016) Onchocerciasis transmission in Ghana: The human blood index of sibling species of the Simulium damnosum complex. Parasites & Vectors Doi: 10.1186/s13071-1703-2

12. Lamberton, P.H.L., Cheke, R.A., Winskill, P., Tirados, I, Walker M., Osei-Atweneboana M.Y, et al. (2015) Onchocerciasis Transmission in Ghana: Persistence under Different Control Strategies and the Role of the Simuliid Vectors. PLoS Negl Trop Dis 9(4): e0003688. doi: 10.1371/journal.pntd.0003688

13. Debrah, A.Y., Specht, S., Klarmann-Schulz, U., Batsa, L., Mand, S., Marfo-Debrekyei, Y., Fimmers, R., Dubben, B., Kwarteng, A., Osei-Atweneboana, M.Y. et al. (2015) Doxycycline Leads to Sterility and Enhanced Killing of Female Onchocerca volvulus Worms in an Area with Persistent Microfilaridermia After Repeated Ivermectin Treatment: A Randomized, Placebo-Controlled, Double-Blind Trial. Clin. Infect. Dis:1-10 

14. Cheke, R. A., Basanez, M.G, Perry, M., White, M.T., Rolf Garms, R., Obuobie, E., Lamberton, P.H.L., Young, S., Osei-Atweneboana M.Y et al. (2015) Potential effects of warmer worms and vectors on onchocerciasis transmission in West Africa. Phil. Trans. R. Soc. B 370: 20130559.

15. Alhassan, A., Makepeace, B. L., LaCourse, E. J., Osei-Atweneboana, M.Y., Carlow, C. K. S., (2014). A Simple Isothermal DNA Amplification Method to Screen Black Flies for Onchocerca volvulus infection. PloS ONE 9(10): e108927. doi: 10.1371/journal.pone.0108927. 

16. Turner, H.C., Walker, M., Churcher, T. S., Osei-Atweneboana, M. Y., Biritwum, N. K., Hopkins, A., Prichard, R.K., Basáñez, M.G. (2014). Reaching the London Declaration on Neglected Tropical Diseases goals for onchocerciasis: an economic evaluation of increasing the frequency of ivermectin treatment in Africa. Clinical infectious diseases; DOI:10.1093/cid/ciu467. 

17. Lamberton, P.H.L., Cheke, R.A., Walker, M., Winskill, P., Osei-Atwenenboana, M. Y., et al. (2014). Onchocerciasis transmission in Ghana: biting and parous rates of host-seeking sibling species of the Simulium damnosum complex. Parasites & Vectors 7:511. 

18. Post, R. J., Cheke, R.A., Boakye, D.A., Wilson, M. D., Osei-Atweneboana, M. Y., et al. (2013). Stability and change in the distribution of cytospecies of the Simulium damnosum complex (Diptera: Simuliidae) in southern Ghana from 1971 to 2011. Parasites & Vectors 6:205. 

19. Turner, H. C., Osei-Atweneboana, M. Y., Walker, M., Tettevi, E. J., Churcher, T. S., et al. (2013). The Cost of Annual versus Biannual Community-Directed Treatment of Onchocerciasis with Ivermectin: Ghana as a Case Study. PLoS Negl Trop Dis 7(9): e2452. doi: 10.1371/journal.pntd.0002452. 

20. Turner, H.C., Churcher, T. S., Walker, M., Osei-Atweneboana, M. Y., Prichard, R. K., et al. (2013). Uncertainty Surrounding Projections of the Long-Term Impact of Ivermectin Treatment on Human Onchocerciasis. PLoS Negl Trop Dis 7(4): e2169. doi: 10.1371/journal.pntd.0002169. 

21. Osei-Atweneboana, M. Y., Boakye, D. A., Awadzi, K., Gyapong, J. O., Prichard, R. K. (2012). Genotypic analysis of Beta-tubulin in Onchocerca volvulus from communities and individuals showing poor parasitological response to ivermectin treatment. International Journal for Parasitology: Drugs and Drug Resistance 2: 20 – 28. 

22. Osei-Atweneboana, M. Y., Lustigman, S., Prichard, R. K., Boatin, B. A., Basanez, M. G. (2012). A Research Agenda for Helminth Diseases of Humans: Health Research and Capacity Building in Disease-Endemic Countries for Helminthiases Control. PLoS Negl Trop Dis 6(4): e1602. doi: 10.1371/journal.pntd.0001602. 

23. Lustigman, S., Geldhof, P., Grant, W. N., Osei-Atweneboana, M. Y., Sripa, B., et al. (2012). A     Research Agenda for Helminth Diseases of Humans: Basic Research and Enabling Technologies to Support Control and Elimination of Helminthiases. PLoS Negl Trop Dis 6 (4): e1445. doi: 10.1371/journal.pntd.0001445. 

24. Wilson, M. D., Osei-Atweneboana, M. Y., Boakye, D. A., Osei-Akoto, I., Obuobi, E., Carl Wiafe, C., Kiszewski, A. (2012). Efficacy of DEET and non-DEET based insect repellents against bites of Simulium damnosum vectors of onchocerciasis.  Med and Vet Ent. doi: 10.1111/j.1365-2915.2012.01054. x. 

25. Boatin, B. A., Basanez, M. G., Prichard, R. K., Awadzi, K., Barakat, R. M., Osei-Atweneboana, M. Y., et al. (2012). A Research Agenda for Helminth Diseases of Humans: Towards Control and Elimination. PLoS Negl Trop Dis 6(4): e1547. doi:10.1371/ journal. pntd.0001547. 

26. Osei-Atweneboana, M. Y., Awadzi, K., Attah, S. K., Boakye, D. A., Gyapong, J. O., Prichard, R. K. (2011). Phenotypic Evidence of Emerging Ivermectin Resistance in Onchocerca volvulus. PLoS Negl Trop Dis 5(3): e998.doi: 10.1371/journal.pntd.0000998. 

27. Churcher, T. S., Pion, S. D. S., Osei-Atweneboana, M.Y., Prichard, R. K., Awadzi, K., Boussinesq., M Collins, R.C., Beatriz Muñoz, B., Whitworth, J.A., Basáñez, M-G. (2009). Identifying sub-optimal responses to ivermectin in the treatment of River Blindness. Proc. Natl. Acad. Sci., USA

28. Taylor, M. J., Awadzi, K., Basanez, M-G., Biritwum, N., Boakye, D., Boatin, B., Bockarie, M., Churcher, T. S., Debrah, A., Edwards, G., Hoerauf, A., Mand, S., Matthews, G., Osei-Atweneboana, M.Y., Prichard, R.K., Wanji, S. Ohene Adjei (2009). Onchocerciasis control: vision for the future from a Ghanaian perspective. Parasites & Vectors 2:1-7

29. Osei-Atweneboana, M. Y., Eng., J. K. L., Boakye, D. A., Gyapong, J. O. and Prichard, R. K. (2007). Prevalence and intensity of Onchocerca volvulus infection and efficacy of ivermectin in endemic communities in Ghana: a two-phase epidemiological study. Lancet, 369:2021-29

30. Osei-Atweneboana, M. Y., Eng., J.K.L., Boakye, D.A., Gyapong, J. O., Prichard, R. K. (2007).  Efficacy of ivermectin against Onchocerca volvulus in Ghana. Lancet 16; 370 (9593): author reply 1123-1124

31. Osei-Atweneboana, M.Y., Eng., J.K.L., Boakye, D.A., Gyapong, J.O., Prichard, R.K., (2007). Efficacy of ivermectin against Onchocerca volvulus in Ghana. Lancet 16; 370 (9593): author reply 1123-1124.

32. Eng., J. K. L., Blackhall, W. J., Osei-Atweneboana, M. Y., Bourguinat, C., Galazzo, D., Beech, R. N., Unnasch, T. R., Awadzi K., Lubega, G. W., and Prichard, R. K. (2006). Ivermectin selection on Beta-tubulin: Evidence in Onchocerca volvulus and Haemonchus contortus. Molecular and Biochemical Parasitology 150 (2):229-35